Sunday, January 22, 2012

Anonymous Deleted CBS.com and Took Down Universal [Hackers]

Taking a shorter break than their last vacation, Anonymous is back at it already. Reports are coming in that they had completely knocked out CBS.com for a good period of time. This wasn't your regular DDoS attack because if you went to CBS.com at the time Anon attacked it, there was nothing except an index page with a single file. Basically, Anonymous gained access to CBS.com and deleted EVERYTHING. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/3XoHlIGG5-A/anonymous-deleted-cbscom

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Love With Food Launches As A Monthly Subscription Service For Gourmet Bites

Love With FoodThe subscription commerce market is heating up with Birch Box, Kiwi Crate, and others all offering various takes on the monthly box model. Today, 500startups company Love With Food is launching its subscription model, which offers a monthly box to users with tasty, gourmet samples of food. Here?s how it works. Through monthly sample boxes, which are $14 per month with free shipping, Love With Food includes 5 or more gourmet tasty bites. The model gives people a way to find and taste samples of new foods before they buy full-size orders. Along with each box, users will get deep discounts on the gourmet food, new recipes that include one or more of the samples, and the opportunity to earn points which can be used for free products.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/pXlWuSPMmEs/

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Saturday, January 21, 2012

Oops ? Sony Ericsson Swings To A 247 Million Euro Loss In Q4 2011

sonySmartphone maker Sony Ericsson this morning posted a pre-tax loss of 247 million euros in the fourth quarter of 2011, after reporting a profit of 31 million euros before taxes in Q3 2011. The company, a 50:50 joint-venture between Sony and Ericsson, blames "intense competition", "price erosion" and effects from the flooding in Thailand as some of the main drivers for the drop.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/9-uQrQdukXs/

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iBoostUp Cleans Out Your Mac's System File Clutter in a Minute [Video]

iBoostUp Cleans Out Your Mac's System File Clutter in a Minute Mac OS X: iBoostUp cleans out the crap on your drive and fine-tunes your system for better performance. It's simple, it's quick, and it's free.

iBoostUp's interface is pretty simple and straightforward. (You can see a quick look at the app in action in the video above.) You're initially brought to a status page that gives you a system overview plus a look at which scans you've run and when. You can click on any of the scans to run them, or access additional options via the sidebar on the left. The Quick Scan option is what will interest most people, as it can save a good chunk of hard disk space in about a minute. It will clear browser cookies, however, which you may not want to delete. You can tell iBoostUp to leave the cookies (or anything else) alone if you want, of course. Your other primary options include Disk Optimizer, which seems to be about the same as running a permissions repair in Disk Utility, and Network Optimizer, which will test your network response times and recommend how you can improve them (if possible).

Overall, the app just handles a few maintenance tasks, but it's a lot faster and simpler than tune-up behemoths like Onyx. If you want something a little less complicated that can speed and clean up your Mac in a minute or two, iBoostUp is worth a look.

iBoostUp (Free) | Mac App Store

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/OHdScCuH6Jc/iboostup-cleans-out-your-macs-system-file-clutter-in-a-minute

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Friday, January 20, 2012

Consultation over Thames airport

The government is to hold a formal consultation on controversial plans for a new airport in the Thames Estuary.

The consultation on the airport, dubbed "Boris Island" because of its backing from London Mayor Boris Johnson, is expected to be announced in March.

Downing Street said no decisions had been made but ministers wanted to explore all options for maintaining the UK's status as a global aviation hub.

The prime minister has previously ruled out any further expansion to Heathrow.

BBC political correspondent Vicki Young said Conservative ministers had previously shown little enthusiasm for the Thames Estuary plan but in recent months that seemed to have changed.

'Major step forward'

In his Autumn Statement, Chancellor George Osborne did not rule out a new hub airport in the Thames Estuary, and this was seen as a clear sign that the government was warming to the scheme, our correspondent said.

Prime Minister David Cameron is said to be supportive of Mr Johnson's alternative to expanding Heathrow, but will await the outcome of the consultation.

Continue reading the main story

PDF download A new airport for London[2 MB]

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Sources close to Mr Johnson said the idea of an airport to the east of London, which would be built partly on reclaimed land, had been gaining ground in conversations with ministers and a formal consultation was a major step forward.

Passenger demand for London's airports is forecast to increase from 140 million passengers a year in 2010 to 400 million passengers a year by 2050, according to a previous report by the Greater London Authority.

Mr Johnson has said the constrictions of Heathrow were becoming "ever more apparent and ever more damaging".

However, concerns have been raised about damage to the environment.

The RSPB, Medway Council and Kent County Council have opposed the Thames Estuary idea, saying it is "undeliverable, unaffordable and unnecessary".

In May last year plans for a third runway and sixth terminal at Heathrow were scrapped when the coalition government took office.

Source: http://www.bbc.co.uk/go/rss/int/news/-/news/uk-politics-16606212

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Combination of oral drugs suppresses common type of hepatitis C

Thursday, January 19, 2012

A new combination of investigational drugs successfully suppressed hepatitis C genotype 1 infection in a high percent of patients who had not responded to previous treatment in a study led by a University of Michigan hepatologist.

The study, which will be published Jan. 19 in the New England Journal of Medicine, focused on hepatitis C genotype 1, which is predominant in the United States and the most difficult to treat. Hepatitis C is a virus that infects the liver and can cause liver cancer and liver cirrhosis. It is transmitted through direct contact with infected blood and blood products.

In this pilot study, patients with hepatitis C genotype 1 infection, who had not responded to previous treatment with PEG-interferon alfa and ribavirin, were given a combination of two investigational direct-acting antiviral agents (daclatasvir and asunaprevir) alone, or were given these two antiviral agents along with PEG-interferon alfa-2a and ribavirin. All the patients saw their hepatitis C viral load drop rapidly, says Anna S. Lok, M.D., professor of Internal Medicine, Division of Gastroenterology at the University of Michigan Medical School and lead author of the study.

All 10 patients given the four drug treatment -- two direct-acting antiviral agents (daclastasvir and asunaprevir) that block the NS3 and NS5A regions of the hepatitis C virus plus PEG-interferon alfa and ribavirin -- had sustained virologic response with undetectable virus at the end of treatment and at 12 weeks after stopping treatment. Four of the 11 patients given the two direct-acting antiviral agents only also achieved sustained virologic response.

A sustained virologic response or SVR means there is no detectable Hepatitis C virus in a patient's blood after treatment is stopped. Achieving sustained virologic response is important, because research has shown that late relapse is rare.

"The two recently approved hepatitis C drugs ? telaprevir or boceprevir -- combined with PEG-interferon alfa and ribavirin have limited success in patients who have not responded to previous treatment with PEG-interferon alfa and ribavirin. Because of this high unmet medical need, there is a necessity for new combination regimens that can increase response rates in that population," says Lok, who also is Director of Clinical Hepatology at U-M. "The high rate of sustained virologic response in patients who received the four drug regimen is very exciting. Although only four of 11 patients given the two direct-acting antiviral agents only achieved sustained virologic response, this is the first study to show that sustained virologic response can be achieved without the use of interferon or ribavirin. These data are very encouraging because PEG-interferon alfaand ribavirin are associated with many side effects and many patients with hepatitis C choose not to receive treatment for fear that they cannot tolerate those drugs."

An estimated 170 million people worldwide are infected with hepatitis C, with genotype 1 being the most prevalent genotype. Up to 80 percent of those infected with hepatitis C will become chronically infected. Twenty percent of people with chronic hepatitis C will develop cirrhosis and, of those, up to 25 percent may progress to liver cancer. Although there is no vaccine to prevent hepatitis C, it is a potentially curable disease.

In the Phase II clinical trial, Lok, along with a team of researchers including scientists from Bristol-Myers Squibb, studied patients with Hepatitis C genotype 1, who had not responded to prior therapy with PEG-interferon alfa and ribavirin. The study was funded by Bristol-Myers Squibb.

"Overall, these results suggest that further research into combinations of direct-acting antiviral agents, with or without PEG-interferon and ribavirin, should be encouraged," Lok says. "Caution must be exercised in selecting the right combination of direct-acting antiviral agents in studies of interferon-free regimens because in this study, all 7 patients who received only two direct-acting antiviral agents that did not achieve sustained virologic response had emergence of drug resistance variants to both drugs."

In this study there were no serious adverse events on treatment or discontinuations due to adverse events. Diarrhea was the most common adverse event in both groups, but it was mild or moderate in all cases.

###

University of Michigan Health System: http://www.med.umich.edu

Thanks to University of Michigan Health System for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 49 time(s).

Source: http://www.labspaces.net/116853/Combination_of_oral_drugs_suppresses_common_type_of_hepatitis_C

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Thursday, January 19, 2012

[OOC] Clash of the Idols

Forum rules
This forum is for OOC discussion about existing roleplays.

Please post all "Players Wanted" threads in the Roleplayers Wanted forum!

This topic is an Out Of Character part of the roleplay, ?Clash of the Idols?. Anything posted here will also show up there.

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Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
This is the auto-generated OOC topic for the roleplay "Clash of the Idols"

You may edit this first post as you see fit.

Jayu, it means freedom <3

User avatar
Jayu
Member for 0 years



I'm Moonlight. The second GM. :)

~ You cannot make the same mistake twice. Once you make it a second time it is no longer a mistake but a choice. ~

I may not post regularly. Please allow me time to complete posts as I am a busy person. Thank you!

User avatar
theMoonlightTheory
Member for 1 years


So I am guessing that one group is all girls and the other all guys or is there a mix in both

The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. (H.P. Lovecraft "The Call of Cthulhu")

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girlwt
Member for 3 years



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